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the drug metabolism and pharmacokinetics quick guide (in English)
Khojasteh,Wong,Hop (Author)
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springer publishing map
· Physical Book
the drug metabolism and pharmacokinetics quick guide (in English) - khojasteh,wong,hop
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Synopsis "the drug metabolism and pharmacokinetics quick guide (in English)"
the drug metabolism and pharmacokinetics, quick guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. it covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.