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Pathogenesis and Treatment of Diabetes Mellitus (in English)
Radder, J. K. ; Lemkes, H. H. P. J. ; Krans, H. M. J. (Author)
·
Springer
· Paperback
Pathogenesis and Treatment of Diabetes Mellitus (in English) - Radder, J. K. ; Lemkes, H. H. P. J. ; Krans, H. M. J.
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Synopsis "Pathogenesis and Treatment of Diabetes Mellitus (in English)"
In this book on diabetes mellitus both the pathogenesis and treat- ment of the disease will be discussed. Pathogenetic studies have led to the distinction between type I and type II diabetes. In type I hyperglycaemia is due predominantly to insulin deficiency; in type II insulin resistance is more important. Three pathogenetic factors are thought to play a role in the etiol- ogy of type I diabetes: heredity, viral infections and immunity. There may be a relationship between these three aspects since genetic pre- disposition changes the susceptibility to viral infections and/or the immunological defence against these infections. Insulitis ensues. Auto- immune processes initiated by this chain of events may contribute to the destruction of the B cells in the islets of Langerhans and diabetes -may eventually follow. This means that at the time of the sudden out- break of the disease, the destructive process has already been active for years.
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The book is written in English.
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