Impact of pharmaceutical care in management and treatment of Vitiligo (in English)
Synopsis "Impact of pharmaceutical care in management and treatment of Vitiligo (in English)"
Vitiligo, also known as leukoderma, is an acquired de-pigmentary disorder characterized by the appearance of white patches resulting from the loss of functional melanocytes and melanin from the skin with worldwide prevalence of approximately 0.1 to 8%. It most often affects the face, elbows and knees, hands and feet, and genitals and is more noticeable in darker-skinned people because of the contrast of white patches against dark skin. The exact etiopathophysiology of Vitiligo is not clearly known, but some main theories exist to explain it: the autoimmune hypothesis, the neural hypothesis, the self-destruct hypothesis (auto cytotoxic), biochemical, oxidative stress, melano-cytorrhagy, and decreased melanocyte survival hypotheses. different treatment modalities of vitiligo like steroidal treatment, chemo-phototherapy, vitamin D analogues, pseudo catalase, vitamin B12, surgical therapy and herbal treatments. Although, there are numerous medical and surgical interventions available to treat vitiligo, there is no study showed a definite treatment measure.Therefore, more randomized controlled trials on the treatment of vitiligo are necessary.Keywords: Vitiligo, Autoimmunity, Melanocyte
