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Impact of Neo-Adjuvant Chemotherapy in Colon Cancer (in English)
Nabila Talbi
(Author)
·
Mourad Abid
(Author)
·
Our Knowledge Publishing
· Paperback
Impact of Neo-Adjuvant Chemotherapy in Colon Cancer (in English) - Talbi, Nabila ; Abid, Mourad
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Synopsis "Impact of Neo-Adjuvant Chemotherapy in Colon Cancer (in English)"
Surgery with adjuvant chemotherapy is currently the gold standard in the management of locally advanced non-metastatic colon cancer. However, a peri-operative strategy is beginning to emerge. The aim of this randomized trial is to report a series of 110 patients operated on for locally advanced non-metastatic colon cancer with evaluation of the impact of neo-adjuvant chemotherapy versus primary surgery in terms of overall survival and recurrence-free survival, with the quality of the complete surgery and histological tumor regression as well as postoperative morbidity and mortality as endpoints. The results show a benefit of neoadjuvant chemotherapy on the quality of surgical excision by down sizing as well as a reduction of major postoperative morbidity and on the anatomopathological results by down staging and partial histological response. There seems to be a superiority of neoadjuvant chemotherapy in terms of median overall survival and recurrence-free survival. This new peri-operative strategy seems to provide tumor control. It would be a kind of pre-enabling for surgery.
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The book is written in English.
The binding of this edition is Paperback.
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