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Formulation of Film Coated Tablets of Norfloxacin and Tinidazole (in English)
Anilkumar Shinde
(Author)
·
Harinath More
(Author)
·
LAP Lambert Academic Publishing
· Paperback
Formulation of Film Coated Tablets of Norfloxacin and Tinidazole (in English) - Shinde, Anilkumar ; More, Harinath
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Synopsis "Formulation of Film Coated Tablets of Norfloxacin and Tinidazole (in English)"
The aim of the present study was development and optimization of an efficacious, pharmaco-economical, palatable and marketable film coated tablet formulation of Norfloxacin-Tinidazole. Bitter taste of both drugs reduces the patient compliance & hence marketability. However it has been shown that film coating technology economical & useful in masking the taste. The core tablets with maximum hardness & minimum disintegration time were selected for film coating. (F-1 & F-07) The optimized formulation F-07 showed hardness, friability, disintegration time and drug release in range 9 kg/cm2, 0.17 0.02%, 27.40 2.1 sec. & 100% release in 30 min. respectively. For all tablet formulation drug release at the end of 30 min was found in the range of 52.78 0.09 to 100.07 0.5 % and from the obtained results, F-07 was selected as an optimized formulation for designing palatable tablet. Therefore it can be concluded that the present work discusses in depth the development and optimization of an efficacious, pharmaco-economical, palatable and marketable tablet formulation of Norfloxacin and Tinidazole.
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The book is written in English.
The binding of this edition is Paperback.
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