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Development of a new generation of artificial heart valve (in English)
Major, Roman (Author)
·
LAP Lambert Academic Publishing
· Paperback
Development of a new generation of artificial heart valve (in English) - Major, Roman
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Synopsis "Development of a new generation of artificial heart valve (in English)"
The project goal is minimizing life-threatening thrombo-emboli formation in pulsatile heart assist devices by a new biomimetic heart valve design based on metal-polymer composites. Heart prostheses support patients with late-stage heart diseases towards recovery or as a bridge to transplantation. In future, they will assist gene therapy to treat myocardial infarction. Besides of deficient blood flow (stagnant zones), state-of-the-art systems with mechanical valves generate platelet activating shear due to a narrow disc-ring gap. The novel composite and valve design solve these pressing medical needs: Injection moulding of polyurethane with a fragile titanium mesh insert combines biologically optimal micro-scale flexibility with macro-stiffness for mechanical function. Added transnational value is joining knowhow in: (1) heart valve design for optimal blood flow, (2) haemo-biofunctional coatings, (3) insert injection moulding, and(4) testing, finally on the artificial patient mode
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The book is written in English.
The binding of this edition is Paperback.
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