Antiepileptic Drug Discovery: Novel Approaches (Methods in Pharmacology and Toxicology) (in English)
Synopsis "Antiepileptic Drug Discovery: Novel Approaches (Methods in Pharmacology and Toxicology) (in English)"
Part I: Novel Approaches for the Treatment of Epilepsy 1. Inflammatory Cytokines as Targets for Epilepsy Drug Therapy María-Leonor López-Meraz, Jesús-Servando Medel-Matus, and Jerome Niquet 2. The Use of Anti-Inflammatory Drugs in Epilepsy María Guadalupe Valle-Dorado, Laura Elena Córdova-Dávalos, Daniel Pérez-Pérez, Rosalinda Guevara-Guzmán, and Luisa Rocha 3. Carbonic Anhydrase and Epilepsy Luciana Gavernet 4. Synaptic Vesicle Protein 2A as a Novel Pharmacological Target with Broad Potential for New Antiepileptic Drugs Luz Adriana Pichardo-Macías, Itzel Jatziri Contreras-García, Sergio R. Zamudio, Edgar Mixcoha, and Julieta G. Mendoza-Torreblanca 5. Do Cannabinoids Represent a Good Therapeutic Strategy for Epilepsy? Cecilia Zavala-Tecuapetla and Luisa Rocha 6. Glutamate Receptors as Targets for Novel Antiepileptic Drug Therapy Manola Cuellar-Herrera, César E. Santana-Gómez, Francia Carmona-Cruz, Daruni Vázquez-Barrón, Francisco Velasco, and Ana L. Velasco 7. Neurosteroid Regulation of Seizures: Role of GABAA Receptor Plasticity Suchitra Joshi and Jaideep Kapur 8. Erythropoietin as Potential Neuroprotective and Antiepileptogenic Agent in Epilepsy and Refractory Epilepsy Amalia Marelli, Liliana Czornyj, Luisa Rocha, and Alberto Lazarowski 9. Caloric Restriction and Dietary Treatments of Epilepsy: Mechanistic Insights for Drug Discovery Karla G. Carvajal Aguilera and Bryan V. Phillips Farfán 10. Gene Therapy in Epilepsy Miguel A. López-García, Iris A. Feria-Romero, Julia J. Segura-Uribe, David Escalante-Santiago, and Sandra Orozco-Suarez Part II: Innovative Solutions for the Screening of New Antiepileptics Drugs and Addressing the Multi-Drug Resistance Issue Epilepsy 11. Human Brain Tissue as a Model for the Study of Epilepsy Leonardo Lara-Valderrábano, Ivette Bañuelos-Cabrera, Víctor Navarrete-Modesto, and Luisa Rocha 12. The Blood-Brain Barrier and the Design of New Antiepileptic Drugs Gabriela Rogel-Salazar and Hiram Luna-Munguia 13. Virtual Screening Applications in the Search of Novel Antiepileptic Drug Candidates Alan Talevi and Luis E. Bruno-Blanch 14. Discovering New Antiepileptic Drugs Addressing the Transporter Hypothesis of Refractory Epilepsy: Ligand-Based Approximations Manuel Couyoupetrou, Mauricio Di Ianni, Melisa Gantner, Guido Pesce, Roxana Peroni, Alan Talevi, and Luis E. Bruno-Blanch 15. Discovering New Antiepileptic Drugs Addressing the Transp
